Helping create the medicines of the future

Welcome to Docking@Home

Docking@Home is Retiring

Our Docking@Home adventure is coming to an end on May 23, 2014. Join us on our next challenge at ExSciTecH.

Docking@Home is a project which uses Internet-connected computers to perform scientific calculations that aid in the creation of new and improved medicines. The project aims to help cure diseases such as Human Immunodeficiency Virus (HIV). Docking@Home is a collaboration between the University of Delaware, The Scripps Research Institute, and the University of California - Berkeley. It is part of the Dynamically Adaptive Protein-Ligand Docking System project and is supported by the National Science Foundation.

How Does It Work?

Before new drugs can be produced for laboratory testing, researchers must create molecular models and simulate their interactions to reveal possible candidates for effective drugs. This simulation is called docking. The combinations of molecules and their binding orientations are infinite in number. Simulating as many combinations as possible requires a tremendous amount of computing power. In order to reduce costs, researchers have decided that an effective means of generating this computing power is to distribute the tasks across a large number of computers.

How Can I Help?

By downloading a free program developed at University of California - Berkeley called BOINC, you can contribute your computer's idle processing cycles to the Docking@Home project. It's safe, easy to setup, and runs only when you want it to so it won't affect your ability to use your computer. If you are interested in finding out more information, you can read more about the project and the science behind it, or if you are ready to help, you can get started below.


Recommended by: seal of approval is Germany's first and so far biggest non-for-profit distributed and grid computing organization. Their goal is to support education, research and science through the use of distributed & grid computing technology


Docking@Home is Retiring
April 07, 2014 17:05 EST

With a heavy heart, we are announcing the retirement of the Docking@Home project. Unfortunately, we no longer have the resources to maintain the project. Starting on April 30, 2014 Docking@Home will no longer be distributing new jobs but will continue to collect results. On May 23, 2014 the server will stop accepting results as the project enters retirement. We hope that you can use this time to p ... (more)

ExSciTech games beta version online!
March 10, 2014 11:05 EST

Explore the molecules that make up the world around us! Challenge yourself to identify them using molecule flashcards game! Build your own question sets to challenge the rest of us! Join us in the ExSciTecH (Exercise, Science, Technology, and Health) project!

ExSciTecH molecule flashcards are live and now in public beta. You can access ExSciTecH here!
... (more)

Docking@Home ligand dataset available for download!
December 23, 2013 17:37 EST

The dataset of sampled ligands generated by Docking@Home with the help of our volunteers is now publicly available for download through this link! It is by far the largest public dataset of docked ligands that have been generated by volunteers’ desktops and laptops. Explore the results we have collected over the pas ... (more)

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Chemical reaction

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